Hari P, Bagga A, Vasudev V, Singh M, Srivastava R N
Department of Paediatrics, All India Institute of Medical Sciences, New Delhi, India.
Pediatr Nephrol. 1995 Aug;9(4):474-5. doi: 10.1007/BF00866731.
The aetiology of nephrolithiasis was investigated in 32 north Indian children (25 boys, 7 girls, mean age 7.9 +/- 3.3 years). An underlying disorder was detected in 16 (50%) patients and included idiopathic hypercalciuria (8 patients), hyperoxaluria (3 patients) and renal tubular acidosis, primary hyperparathyroidism and hyperuricosuria (1 patient each). Magnesium ammonium phosphate calculi were found in 2 patients with recurrent urinary tract infections, 1 of whom had a duplex pelvic collecting system. In 16 patients (50%) a cause for renal calculi was not identified. Our findings suggest that an underlying disorder is present in a large proportion of children with nephrolithiasis where appropriate treatment may be beneficial.
对32名印度北部儿童（25名男孩，7名女孩，平均年龄7.9±3.3岁）的肾结石病因进行了调查。在16名（50%）患者中检测到潜在疾病，包括特发性高钙尿症（8例）、高草酸尿症（3例）以及肾小管酸中毒、原发性甲状旁腺功能亢进和高尿酸尿症（各1例）。2例复发性尿路感染患者发现有磷酸镁铵结石，其中1例有重复肾盂集合系统。16名（50%）患者未发现肾结石病因。我们的研究结果表明，大部分肾结石儿童存在潜在疾病，适当治疗可能有益。
