Kurwa H A, Marks R
Department of Dermatology, University of Wales College of Medicine, Heath Park, Cardiff, U.K.
Br J Dermatol. 1995 Oct;133(4):625-9. doi: 10.1111/j.1365-2133.1995.tb02717.x.
We report two patients with skin disorders usually associated with severe immunosuppression, who had low CD4+ lymphocyte counts but normal immunoglobulin levels. The patients were HIV negative, and had CD4+ lymphocyte counts just above 300/mm3, but they presented with cutaneous manifestations of profound immunodeficiency. Idiopathic CD4+ lymphocyte deficiency is a recently described syndrome which may present with dermatological disease. We discuss the symptom complex of our patients in relationship to the diagnosis of idiopathic CD4+ lymphocyte deficiency.
我们报告了两名患有通常与严重免疫抑制相关的皮肤疾病的患者，他们的CD4+淋巴细胞计数较低，但免疫球蛋白水平正常。这两名患者HIV检测呈阴性，CD4+淋巴细胞计数略高于300/mm3，但却出现了严重免疫缺陷的皮肤表现。特发性CD4+淋巴细胞缺乏症是一种最近描述的综合征，可能会出现皮肤病。我们结合特发性CD4+淋巴细胞缺乏症的诊断来讨论我们患者的症状复合体。
