Hourihane J, Hodges E, Smith J, Keefe M, Jones A, Connett G
University of Southampton, University Hospitals NHS Trust, UK.
Arch Dis Child. 1999 Jan;80(1):77-9. doi: 10.1136/adc.80.1.77.
A sister (aged 6 years) and brother (aged 8 years) presented four months apart with severe molluscum contagiosum. Both children demonstrated clinical and laboratory evidence of combined immunodeficiency. The extent of skin involvement by molluscum contagiosum precluded conventional treatment as well as intralesional interferon alpha (IFN alpha). Both subjects responded well to subcutaneous IFN alpha.
一名6岁的妹妹和一名8岁的弟弟先后间隔4个月出现严重的传染性软疣。两个孩子都有联合免疫缺陷的临床和实验室证据。传染性软疣累及皮肤的范围使传统治疗以及皮损内注射α干扰素(IFNα)无法实施。两名患者对皮下注射IFNα均反应良好。