Wollenberg A, Peter R U, Przybilla B
Department of Dermatology, Ludwig-Maximilians-University, Munich, Germany.
Br J Dermatol. 1995 Oct;133(4):644-6. doi: 10.1111/j.1365-2133.1995.tb02722.x.
Basalomatosis is an uncommon skin condition characterized by the occurrence of multiple basal cell carcinomas. Many cases reported in the literature have been attributed to arsenic treatment in psoriasis patients. We report a patient with basalomatosis caused by cobalt-60 (60Co) irradiation. A 55-year-old farmer developed 43 basal cell carcinomas 20 years after treatment of an immunoblastoma with 60Co irradiation. All the tumours were located within the radiation fields. Other possible causes of basalomatosis, such as arsenic intoxication and basal cell naevus syndrome, were excluded. The patient's multiple superficial basal cell carcinomas probably represent a late adverse effect of the 60Co irradiation.
基底细胞癌病是一种罕见的皮肤病,其特征是出现多发性基底细胞癌。文献中报道的许多病例都归因于银屑病患者接受砷治疗。我们报告了一例由钴 - 60(60Co)照射引起的基底细胞癌病患者。一名55岁的农民在接受60Co照射治疗免疫母细胞瘤20年后出现了43个基底细胞癌。所有肿瘤均位于放射野内。排除了基底细胞癌病的其他可能原因,如砷中毒和基底细胞痣综合征。该患者的多发性浅表基底细胞癌可能是60Co照射的晚期不良反应。