Fink P, Rogers M A, Korge B, Winter H, Schweizer J
German Cancer Research Center, Research Program 2 (Tumor Cell Regulation), Heidelberg, Germany.
Biochim Biophys Acta. 1995 Oct 17;1264(1):12-4. doi: 10.1016/0167-4781(95)00122-w.
A full-length cDNA of a human type I hair keratin was isolated that encodes a protein of 416 amino acids. Northern blot analysis shows that the mRNA is present in human scalp but not in hairless skin. Based on sequence homology comparisons with the four known mouse type I hair keratins mHal-4 the keratin could be identified as the human hair keratin hHal.
分离出了一种人类I型毛发角蛋白的全长cDNA，它编码一种含有416个氨基酸的蛋白质。Northern印迹分析表明，该mRNA存在于人类头皮中，但不存在于无毛皮肤中。基于与四种已知小鼠I型毛发角蛋白mHal-4的序列同源性比较，该角蛋白可被鉴定为人类毛发角蛋白hHal。
