Hambrecht M
Central Institute of Mental Health, Mannheim, Germany.
Eur Arch Psychiatry Clin Neurosci. 1995;245(4-5):267-9. doi: 10.1007/BF02191807.
Comparing reports on emerging symptomatology of schizophrenia by families with and without a prior case of the disorder shows that experienced families are more sensitive to delusions and hallucinations; however, they observe unspecific, affective, negative, and social/behavioral symptoms less adequately than relatives who have no previous case of schizophrenia in their families. The results only partly support the hypothesis that already-affected families tend to deny a second case. A contrast effect of the first psychosis over the second case (as long as it is prepsychotic) appears to be plausible also.
比较有精神分裂症既往病例和无精神分裂症既往病例的家庭关于精神分裂症新出现症状的报告表明，有经验的家庭对妄想和幻觉更敏感；然而，与家中无精神分裂症既往病例的亲属相比，他们对非特异性、情感性、阴性以及社会/行为症状的观察不够充分。这些结果仅部分支持已患病家庭倾向于否认出现第二例病例这一假说。首次精神病对第二例病例（只要处于精神病前期）的对比效应似乎也有道理。
