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[评估光动力效应在风湿病学中的应用可能性]

[Assessment of the possibility of using the photodynamic effect in rheumatology].

作者信息

Tauraĭtis V A, Shishporenok S I, Grubina L A, Sarzhevskaia M V, Gurinovich I F, GGurinovich G P, Matulis A A

出版信息

Biofizika. 1992 Mar-Apr;37(2):345-51.

PMID:7578326
Abstract

Results of the analysis of a number of parameters which determine the efficiency of using the photodynamic action for treating rheumatoid arthritis are reported. The investigations are based on determining the character of sensitizer stabilization in the joint tissue and evaluating its stability. As the sensitizer chlorin e6 was chosen. We have established the fact of contrast accumulation of chlorin e6 in the synovial membrane and cartilage, developed the system of intrajoint introduction of the pigment, studied the kinetics of sensitizer destruction under irradiation.

摘要

报告了对一些决定光动力作用治疗类风湿性关节炎效率的参数的分析结果。这些研究基于确定关节组织中敏化剂的稳定特性并评估其稳定性。选择了二氢卟吩e6作为敏化剂。我们已经确定了二氢卟吩e6在滑膜和软骨中对比积累的事实,开发了关节内引入色素的系统,研究了辐照下敏化剂破坏的动力学。

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