Ikizler T A, Wingard R L, Hakim R M
Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee 37232-2372, USA.
Perit Dial Int. 1995;15(5 Suppl):S63-6.
It is clear that malnutrition is common in chronic dialysis patients and is associated with increased morbidity and mortality. Evidence is accumulating that several measures can be taken to improve the nutritional status of these patients. An early start of dialysis, an increase in dialysis dose, the use of biocompatible membranes or dialysis solutions, and intensive nutritional counseling should be applied when necessary. If these measures fail, additional interventions, such as parenteral or enteral nutritional supplements, rhGH, and rhIGF-1, alone or in combination, should be tried.
很明显,营养不良在慢性透析患者中很常见,并且与发病率和死亡率的增加相关。越来越多的证据表明,可以采取多种措施来改善这些患者的营养状况。必要时应尽早开始透析、增加透析剂量、使用生物相容性膜或透析液,并进行强化营养咨询。如果这些措施无效,应尝试其他干预措施,如单独或联合使用肠外或肠内营养补充剂、重组人生长激素(rhGH)和重组胰岛素样生长因子-1(rhIGF-1)。