van Straalen J P, Leyte A, Weber J A, Gorgels J P, Sanders G T
Laboratorium voor Algemene Klinische Chemie, Academisch Ziekenhuis bij de Universiteit van Amsterdam, The Netherlands.
Eur J Clin Chem Clin Biochem. 1995 May;33(5):315-22. doi: 10.1515/cclm.1995.33.5.315.
The Boehringer Mannheim Hitachi 911 is a selective analyzer for 35 different methods including 3 ion-selective electrode (ISE) methods. We have evaluated this analyzer primarily to obtain objective information on its applicability for routine urine analyses in our laboratory. We also implemented appropriate assays for various special serum- and whole blood-tests, some for the first time on the Hitachi 911 and some with modified settings. Analytical evaluation involved NCCLS EP5-T2 (imprecision), NCCLS EP6-P (linearity), Krouwer 27 (multifactor) and Passing & Bablok (method comparison) evaluation protocols. With the exception of evidence of systematic erroneous sample predilution, overall results were favourable. Practicability of the Hitachi 911 was judged by simulating daily routine. During a period of two weeks, daily urine samples were rerun on the Hitachi 911, leading to a gain of about 50% in total processing time. It was concluded that the Hitachi 911 meets the requirements in terms of analytical performance, reliability, versatility and speed for an analyzer to be used in a routine (urine) setting, while having a distinct role in special (serum/whole blood) measurements.
勃林格曼海姆日立911型分析仪是一款具有35种不同检测方法的选择性分析仪，其中包括3种离子选择电极（ISE）方法。我们对这款分析仪进行评估，主要是为了获取关于其在我们实验室用于常规尿液分析适用性的客观信息。我们还针对各种特殊的血清和全血检测实施了适当的检测方法，有些检测方法是首次在日立911型分析仪上使用，有些则是采用了修改后的设置。分析评估涉及NCCLS EP5-T2（不精密度）、NCCLS EP6-P（线性）、Krouwer 27（多因素）以及帕欣和巴布洛克（方法比较）评估方案。除了存在系统性错误样本预稀释的证据外，总体结果令人满意。通过模拟日常常规操作来判断日立911型分析仪的实用性。在两周的时间里，每天的尿液样本都在日立911型分析仪上重新检测，使得总处理时间增加了约50%。得出的结论是，日立911型分析仪在分析性能、可靠性、多功能性和速度方面满足在常规（尿液）检测环境中使用的分析仪的要求，同时在特殊（血清/全血）检测中具有独特作用。
