Straussberg R, Sirota L, Hart J, Amir Y, Djaldetti M, Bessler H
Department of Pediatrics, Hasharon Hospital, Golda Medical Center, Petah Tiqva, Israel.
Biol Neonate. 1995;68(1):15-8. doi: 10.1159/000244212.
The effect of colostrum of mothers of preterm and full-term newborns on the phagocytic activity for latex particles by normal peripheral blood polymorphonuclear cells was examined. The results showed that human colostrum contains a phagocytosis-promoting factor(s), which not only increases the number of phagocytic cells, but also stimulates the phagocytic activity of the individual cell. This factor(s) was more active in preterm colostrum. Thus, while term colostrum increased the number of phagocytic cells by 95% in comparison with the control, preterm colostrum enhanced the number of phagocytic cells by 300%. Similarly, term colostrum increased the phagocytic capacity of the individual cell by 51%, whereas preterm colostrum by 137%. The difference between the results in all experimental points was statistically highly significant.
研究了早产和足月新生儿母亲的初乳对正常外周血多形核细胞吞噬乳胶颗粒活性的影响。结果表明，人初乳含有一种或多种促吞噬因子，它不仅能增加吞噬细胞的数量，还能刺激单个细胞的吞噬活性。这种因子在早产初乳中更具活性。因此，与对照组相比，足月初乳使吞噬细胞数量增加了95%，而早产初乳使吞噬细胞数量增加了300%。同样，足月初乳使单个细胞的吞噬能力提高了51%，而早产初乳提高了137%。所有实验点结果之间的差异在统计学上具有高度显著性。
