Kon M, Ishikawa K, Miyamoto Y, Asaoka K
Department of Dental Engineering, School of Dentistry, Tokushima University, Japan.
Biomaterials. 1995 Jun;16(9):709-14. doi: 10.1016/0142-9612(95)99699-m.
A functional gradient bioceramic that can function gradually with respect to body tissue was studied by changing the composition of calcium phosphate gradually from the surface to the inside. Diamond powder was spread on the surface of compact hydroxyapatite (HA) powder and fired at 1280 degrees C under reduced pressure, followed by firing under atmospheric conditions. The sintered body thus prepared was dense and alpha-tricalcium phosphate (alpha-TCP: alpha-Ca3(PO4)2) was found on its surface. The content of alpha-TCP gradually decreased with increasing depth from the surface. In contrast, the content of HA increased with increasing depth from the surface. The gradient ratio of alpha-TCP and HA depends on the firing time for each condition, i.e. reduced or atmospheric pressure. The alpha-TCP formation was ascribed to the decomposition of HA due to the spontaneous combustion of diamond powder.
通过从表面到内部逐渐改变磷酸钙的组成，研究了一种能相对于身体组织逐渐发挥功能的功能梯度生物陶瓷。将金刚石粉末散布在致密羟基磷灰石（HA）粉末表面，在减压下于1280℃烧制，然后在大气条件下烧制。由此制备的烧结体致密，并且在其表面发现了α-磷酸三钙（α-TCP：α-Ca3(PO4)2）。α-TCP的含量随着从表面到内部深度的增加而逐渐降低。相反，HA的含量随着从表面到内部深度的增加而增加。α-TCP和HA的梯度比取决于每种条件下的烧制时间，即减压或常压条件。α-TCP的形成归因于金刚石粉末自燃导致的HA分解。
