Bouayad Z, Aichane A, Trombati N, Amrani S, Bahlaoui A
Service de Pneumologie, Hôpital du 20 Août, Casablanca, Maroc.
Tuber Lung Dis. 1995 Aug;76(4):367-9. doi: 10.1016/s0962-8479(05)80038-3.
The aim of this prospective study was to evaluate the results of a four-month regimen (2HRZ/2HR) in the treatment of isolated tuberculous pleurisy with effusion. It included 68 patients presenting with histologically confirmed tuberculous pleurisy treated with 2HRZ/2HR, physiotherapy and aspiration of the pleura. Patients were seen every 2 months during treatment, and then 1, 3, 4, 6, 12, and 24 months after the end of treatment. Preliminary results show a favourable response in 58 patients (85%) and minimal pleural thickening in 10 patients. There were no failures, no relapses nor any extrapleural dissemination after a follow-up period of on average 20 months. These encouraging results need to be evaluated in a long-term study.
这项前瞻性研究的目的是评估为期四个月的治疗方案(2HRZ/2HR)治疗单纯性结核性胸膜炎伴胸腔积液的效果。该研究纳入了68例经组织学确诊为结核性胸膜炎的患者,采用2HRZ/2HR方案、物理治疗及胸腔穿刺抽液进行治疗。治疗期间每2个月对患者进行一次检查,治疗结束后1、3、4、6、12及24个月也进行检查。初步结果显示,58例患者(85%)反应良好,10例患者胸膜增厚轻微。平均随访20个月后,无治疗失败、复发及胸膜外播散情况。这些令人鼓舞的结果需要在长期研究中进行评估。