De Robertis E M, Fainsod A, Gont L K, Steinbeisser H
Department of Biological Chemistry, University of California, Los Angeles 90024-1737, USA.
Dev Suppl. 1994:117-24.
The availability of molecular markers now permits the analysis of the common elements of vertebrate gastrulation. While gastrulation appears to be very diverse in the vertebrates, by analyzing a head-organizer marker, goosecoid, and a marker common to all forming mesoderm, Brachyury, we attempt to identify homologous structures and equivalent stages in Xenopus, zebrafish, chick and mouse gastrulation. Using a tail-organizer marker, Xnot-2, we also discuss how the late stages of gastrulation lead to the formation of the postanal tail, a structure characteristic of the chordates.
分子标记的可用性现在使得对脊椎动物原肠胚形成的共同要素进行分析成为可能。虽然原肠胚形成在脊椎动物中似乎非常多样，但通过分析一种头部组织者标记物——鹅膏菌素，以及所有正在形成的中胚层共有的一种标记物——短尾蛋白，我们试图在非洲爪蟾、斑马鱼、鸡和小鼠的原肠胚形成过程中识别同源结构和等效阶段。使用一种尾部组织者标记物Xnot-2，我们还讨论了原肠胚形成的后期阶段如何导致肛门后尾的形成，肛门后尾是脊索动物的一种特征性结构。
