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[二硫化碳实验作用下的溶酶体和细胞质酶活性]

[Lysosomal and cytoplasmic enzymatic activity under the experimental action of carbon disulfide].

作者信息

Merkur'eva R V, Bushinskaia L I, Aulika B V, Shaternikova I S, Protsenko E I

出版信息

Vopr Med Khim. 1978 Mar-Apr;24(2):151-6.

PMID:758094
Abstract

Activity of lysosomal enzymes and content of carbohydrate containing biopolymers (glycosaminoglycans, glycoproteins) were altered in various tissues (liver, kidney, brain, aorta) of experimental animals intoxicated with carbon disulfide. Possible role of the impairments observed, related to neurotropic and hepatotoxic effects, is discussed. Subsequent development of atherogenic and embryotoxic effects of carbon disulfide--one of contaminators of surroundings--are considered.

摘要

在二硫化碳中毒的实验动物的各种组织(肝脏、肾脏、大脑、主动脉)中,溶酶体酶的活性以及含碳水化合物的生物聚合物(糖胺聚糖、糖蛋白)的含量发生了改变。讨论了所观察到的损伤与神经毒性和肝毒性作用相关的可能作用。还考虑了二硫化碳(环境污染物之一)致动脉粥样硬化和胚胎毒性作用的后续发展。

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[Lysosomal and cytoplasmic enzymatic activity under the experimental action of carbon disulfide].[二硫化碳实验作用下的溶酶体和细胞质酶活性]
Vopr Med Khim. 1978 Mar-Apr;24(2):151-6.
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