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[毒性物质对动物机体作用中的空洞性和壁层消化]

[Cavitary and parietal digestion in the action of a toxic agent on the animal organism].

作者信息

Murashko V A, Tantsiura E M

出版信息

Vopr Pitan. 1977 Nov-Dec(6):32-6.

PMID:602101
Abstract

In rats exposed to a long-term effect of carbon disulphide vapours in concentrations of 10 and 100 mg/m3 of air subject to a dynamic study were the activity of the enterokinase and alkaline phosphatase of the small intestine mucosa and feces, the presence of protein of non-alimentary origin and of the mucus in feces, coprocytograms, this being accompanied by a histomorphological verification of the microflora. In rats exposed to the effect of carbon disulphide in concentrations of 50 and 200 mg/m3 the studies covered parietal digestion by using as substrates carbohydrates and dipeptide. The degree of pathology was found to depend on the concentration of the toxic agent and the duration of priming.

摘要

对暴露于浓度为10和100毫克/立方米空气中二硫化碳蒸气长期影响下的大鼠进行了动态研究,观察指标包括小肠黏膜和粪便中肠激酶和碱性磷酸酶的活性、粪便中非食物源性蛋白质和黏液的存在情况、粪便细胞图谱,同时还对微生物群进行了组织形态学验证。对暴露于浓度为50和200毫克/立方米二硫化碳影响下的大鼠,以碳水化合物和二肽为底物研究了壁内消化情况。结果发现病理程度取决于有毒物质的浓度和引发时间。

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