Geiduschek E P, Bardeleben C, Joazeiro C A, Kassavetis G A, Whitehall S
Department of Biology, University of California, San Diego, La Jolla 92093-0634, USA.
Braz J Med Biol Res. 1995 Feb;28(2):147-59.
In this article we review and summarize salient features of the mechanism of transcription by eukaryotic RNA polymerase III, focusing a considerable part of the account on the work of our laboratory, dealing with Saccharomyces cerevisiae, but emphasizing properties that are common to all eukaryotic RNA polymerases. The following topics are briefly discussed: promoter structure; transcription factors; internal structure of transcription complexes and DNA-protein interactions; U6 genes; promoter opening and RNA chain elongation; hydrolytic RNA retraction.
在本文中，我们回顾并总结了真核生物RNA聚合酶III转录机制的显著特征，相当一部分内容聚焦于我们实验室以酿酒酵母为研究对象的工作，但同时强调所有真核生物RNA聚合酶共有的特性。以下主题将简要讨论：启动子结构；转录因子；转录复合物的内部结构及DNA-蛋白质相互作用；U6基因；启动子解链与RNA链延伸；水解性RNA回缩。
