Boĭko V N, Zholus R B, Legeza V I
Radiats Biol Radioecol. 1995 Jul-Aug;35(4):522-7.
In experiments with mice three kinds of dose dependence of radioprotection efficiency were shown for different radioprotectors. Maximum protection was revealed in the ranges of LD70-100/30 for naphthyzin and cystamine, LD50-70/30 for thymogen and lymphokinin, LD70/30 for prodigiosan and polyribonate. The necessity of research of preparations which increase radioresistance in the wide range of doses is pointed. The problem of improved criteria for radioprotector selection is discussed.
在对小鼠进行的实验中,针对不同的辐射防护剂显示出了三种辐射防护效率的剂量依赖性。对于萘嗪和胱胺,在LD70 - 100/30范围内显示出最大保护作用;对于胸腺生成素和淋巴细胞激活素,在LD50 - 70/30范围内;对于灵菌红素和聚核糖核苷酸,在LD70/30范围内。指出了研究在广泛剂量范围内提高抗辐射性的制剂的必要性。讨论了改进辐射防护剂选择标准的问题。