蛋白水解作用。蛋白酶体：一种蛋白质降解细胞器？
Proteolysis. The proteasome: a protein-degrading organelle?
作者信息
Rubin D M, Finley D
机构信息
Department of Cell Biology, Harvard Medical School, Boston, Massachusetts 02115, USA.
出版信息
Curr Biol. 1995 Aug 1;5(8):854-8. doi: 10.1016/s0960-9822(95)00172-2.
PMID:7583140
Abstract
The crystal structure of the proteasome suggests that degradation of ubiquitin-protein conjugates is achieved by unfolding the protein substrate and translocating it through a channel into a peptidase-containing chamber.
摘要
蛋白酶体的晶体结构表明，泛素化蛋白偶联物的降解是通过使蛋白质底物解折叠并将其通过一个通道转运到含有肽酶的腔室中实现的。
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