Verrouil E, Mazieres B
Department of Rheumatology, Rangueil Teaching Hospital, Toulouse, France.
Rev Rhum Engl Ed. 1995 Jun;62(6 Suppl 1):9S-13S.
Etiological factors in finger osteoarthritis are both local (single injury or repetitive joint use) and general. Epidemiological studies, twin studies, and studies of the ethnic influence have established that genetic factors play a role. The disease is more common in postmenopausal women, suggesting an influence of hormonal factors. Findings from studies of associations between finger osteoarthritis and osteoarthritis at other sites (spine, hips, knees), hyperostosis, and obesity, as well as the fact that the disease is less common in patients with osteoporosis and absent in hemiplegia, suggest that the concept of "osteoarthritic disease" is relevant.
手指骨关节炎的病因既有局部因素（单次损伤或关节反复使用），也有全身因素。流行病学研究、双胞胎研究以及种族影响研究均证实遗传因素起一定作用。该疾病在绝经后女性中更为常见，提示激素因素的影响。手指骨关节炎与其他部位（脊柱、髋部、膝部）骨关节炎、骨质增生及肥胖之间关联的研究结果，以及该疾病在骨质疏松患者中较少见且在偏瘫患者中不存在这一事实，表明“骨关节炎性疾病”这一概念是相关的。
