RNA折叠

RNA folding.

作者信息

Pyle A M, Green J B

机构信息

Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA.

出版信息

Curr Opin Struct Biol. 1995 Jun;5(3):303-10. doi: 10.1016/0959-440x(95)80091-3.

DOI:10.1016/0959-440x(95)80091-3

PMID:7583628

Abstract

The number of known motifs for RNA folding and RNA tertiary organization is expanding rapidly as we learn more about the diverse biological functions of RNA. Problems in protein and RNA folding have melded in recent investigations of ribonucleoprotein folding. Theoretical and experimental models are rapidly being developed for the pathways and stabilizing forces involved in RNA folding.

摘要

随着我们对RNA多样生物学功能的了解不断深入，已知的RNA折叠和RNA三级结构基序的数量正在迅速增加。在核糖核蛋白折叠的最新研究中，蛋白质和RNA折叠问题相互交织。针对RNA折叠所涉及的途径和稳定作用力，理论和实验模型正在迅速建立。