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用兔抗胸腺细胞和白血病细胞抗血清检测到的大鼠淋巴细胞分化抗原。

Rat lymphocyte differentiation antigens detected by rabbit antiserum to thymocytes and leukaemic cells.

作者信息

Thompson A, Morris R J

出版信息

Immunology. 1977 Apr;32(4):419-25.

Abstract

The lymphocyte differentiation antigens detected by rabbit antisera to rat thymocytes and leukaemic cells have been investigated. Thy-1 was the only such antigen detected by the anti-thymocyte serum, which was predominately directed to two xenoantigenic determinants rather than the Thy-1.1 determinant on this molecule. Two additional antigens were recognized by the anti-leukaemia serum. One of these was found on thymocytes and peripheral lymphocytes, but only on 1 per cent of bone marrow cells. The other was found not only on lymphocytes, but also on the nucleated myeloid and erythroid cells of bone marrow.

摘要

对用兔抗大鼠胸腺细胞和白血病细胞血清检测到的淋巴细胞分化抗原进行了研究。抗胸腺细胞血清检测到的此类抗原中,Thy-1是唯一的一种,该血清主要针对该分子上的两个异种抗原决定簇,而非Thy-1.1决定簇。抗白血病血清识别出另外两种抗原。其中一种在胸腺细胞和外周淋巴细胞上发现,但仅在1%的骨髓细胞上存在。另一种不仅在淋巴细胞上发现,也在骨髓有核髓细胞和红细胞上发现。

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