Merkle J, Zeller H
J Pharm Sci. 1979 Jan;68(1):100-2. doi: 10.1002/jps.2600680133.
Povidone-iodine USP was tested for mutagenicity in mice by the dominant lethal assay or micronucleus test and in Chinese hamsters by the bone marrow test. None of the three tests revealed any evidence of mutagenic effect.
采用显性致死试验或微核试验对美国药典聚维酮碘进行小鼠致突变性测试,并采用骨髓试验对中国仓鼠进行测试。三项试验均未显示出任何诱变作用的证据。