Elsayed M A, Abdine H, Elsayed Y M
J Pharm Sci. 1979 Jan;68(1):9-11. doi: 10.1002/jps.2600680107.
Minophylline (theophylline ethanoate of piperazine) and aminophylline (theophylline ethylenediamine) were determined spectrophotometrically in dosage forms without interference from excipients and/or preservatives. A mixture of minophylline, in about 30-fold concentration, with phenobarbital was assayed for both components with good accuracy and high reproducibility.
采用分光光度法测定了剂型中的氨茶碱(哌嗪的茶碱乙酸盐)和茶碱(茶碱乙二胺),不受辅料和/或防腐剂的干扰。对氨茶碱与约30倍浓度的苯巴比妥的混合物中的两种成分进行了测定,准确度高,重现性好。