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分光光度法测定茶碱制剂。

Spectrophotometric determination of theophylline formulations.

作者信息

Elsayed M A, Abdine H, Elsayed Y M

出版信息

J Pharm Sci. 1979 Jan;68(1):9-11. doi: 10.1002/jps.2600680107.

DOI:10.1002/jps.2600680107
PMID:758474
Abstract

Minophylline (theophylline ethanoate of piperazine) and aminophylline (theophylline ethylenediamine) were determined spectrophotometrically in dosage forms without interference from excipients and/or preservatives. A mixture of minophylline, in about 30-fold concentration, with phenobarbital was assayed for both components with good accuracy and high reproducibility.

摘要

采用分光光度法测定了剂型中的氨茶碱(哌嗪的茶碱乙酸盐)和茶碱(茶碱乙二胺),不受辅料和/或防腐剂的干扰。对氨茶碱与约30倍浓度的苯巴比妥的混合物中的两种成分进行了测定,准确度高,重现性好。

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