Leung D Y, Meissner H C, Fulton D R, Quimby F, Schlievert P M
Division of Pediatric Allergy-Immunology, National Jewish Center for Immunology and Respiratory Medicine, Denver, Colorado 80206, USA.
Clin Immunol Immunopathol. 1995 Nov;77(2):119-26. doi: 10.1006/clin.1995.1134.
Kawasaki syndrome (KS) is an acute multisystem vasculitis of infancy and early childhood associated with the development of myocarditis and coronary artery abnormalities. Despite the widely held belief that KS is caused by an infectious agent, there remains considerable controversy over its etiology. Recent immunologic and microbiologic studies suggest a potential role for staphylococcal and streptococcal toxins (superantigens) in the pathogenesis of KS. Confirmation of these findings could result in more effective diagnostic and therapeutic approaches to this common cause of acquired heart disease in children.
川崎病（KS）是一种发生于婴幼儿期的急性多系统血管炎，与心肌炎和冠状动脉异常的发生有关。尽管人们普遍认为KS由感染因子引起，但其病因仍存在很大争议。最近的免疫学和微生物学研究表明，葡萄球菌和链球菌毒素（超抗原）在KS的发病机制中可能起作用。这些发现若得到证实，可能会为儿童后天性心脏病这一常见病因带来更有效的诊断和治疗方法。
