Andrassy K
Department of Internal Medicine, University Hospital, Heidelberg, Germany.
Diagn Microbiol Infect Dis. 1995 May-Jun;22(1-2):85-7. doi: 10.1016/0732-8893(95)00086-p.
A literature review was carried out to assess the effect of hemodialysis, hemofiltration, and continuous ambulatory peritoneal dialysis on the pharmacokinetics of cefotaxime, particularly in patients with severe renal impairment. It was concluded that the dosage of cefotaxime, adjusted for renal function, would require no further adjustment during peritoneal dialysis or hemofiltration.
进行了一项文献综述，以评估血液透析、血液滤过和持续性非卧床腹膜透析对头孢噻肟药代动力学的影响，特别是对严重肾功能损害患者的影响。得出的结论是，经肾功能调整后的头孢噻肟剂量在腹膜透析或血液滤过期间无需进一步调整。
