Kearney T J, Shabot M M
Department of Surgery, Cedars-Sinai Medical Center, Los Angeles, USA.
Chest. 1995 Nov;108(5):1349-52. doi: 10.1378/chest.108.5.1349.
This study was designed to determine the incidence rate, define risk factors, and suggest proper management protocols for pulmonary artery (PA) rupture associated with Swan-Ganz catheters.
This is a retrospective chart-review study.
This study involved 32,442 inpatients requiring hemodynamic monitoring with Swan-Ganz catheters in the operating rooms and ICUs at a large, private teaching hospital over a 17-year period (1975 to 1991).
Ten patients sustained PA rupture, yielding an observed rupture rate of 0.031% of catheter insertions. All ten patients had hemoptysis and five (50%) had pulmonary hypertension. Two patients (20%) had undergone anticoagulation at the time of rupture. Four of the six surgical patients were still in surgery at the first sign of rupture. A thoracotomy was performed in five patients. We noted a trend toward survival with thoracotomy, but it was not statistically significant. The overall mortality rate was 70%. When data from our 10 patients were combined with 65 patients from the literature, we found that thoracotomy was essential for survival in patients with hemothorax. There were no survivors among seven patients with hemothorax simply observed, compared with eight (50%) survivors in 16 patients undergoing thoracotomy (p = 0.026). Thirty-nine (75%) of 52 patients without hemothorax survived, whether or not a thoracotomy was performed.
Our study suggested that the incidence of Swan-Ganz catheter-associated PA rupture is 0.031% and that an urgent thoracotomy should be performed if hemothorax is present at any point.
本研究旨在确定与Swan-Ganz导管相关的肺动脉(PA)破裂的发生率,明确危险因素,并提出适当的管理方案。
这是一项回顾性图表审查研究。
本研究纳入了1975年至1991年期间在一家大型私立教学医院的手术室和重症监护病房中,32442例需要使用Swan-Ganz导管进行血流动力学监测的住院患者。
10例患者发生PA破裂,导管插入的观察破裂率为0.031%。所有10例患者均有咯血,5例(50%)有肺动脉高压。2例患者(20%)在破裂时接受了抗凝治疗。6例手术患者中有4例在破裂的最初迹象出现时仍在手术中。5例患者进行了开胸手术。我们注意到开胸手术有生存趋势,但无统计学意义。总死亡率为70%。当将我们10例患者的数据与文献中的65例患者的数据相结合时,我们发现开胸手术对于血胸患者的生存至关重要。单纯观察的7例血胸患者中无幸存者,而16例接受开胸手术的患者中有8例(50%)存活(p = 0.026)。52例无血胸的患者中,无论是否进行开胸手术,39例(75%)存活。
我们的研究表明,Swan-Ganz导管相关PA破裂的发生率为0.031%,如果在任何时候出现血胸,应紧急进行开胸手术。