Borchardt C M, Bernstein G A
University of Minnesota Medical School, Minneapolis, USA.
Child Psychiatry Hum Dev. 1995 Fall;26(1):11-8. doi: 10.1007/BF02353226.
This study examined comorbid psychiatric disorders in adolescents with bipolar disorder. Hospitalized bipolar adolescents (N = 10) were compared to hospitalized adolescents with unipolar depression (N = 33), and to adolescents with nonaffective psychiatric disorders (N = 11). Results showed conduct disorder, attention-deficit hyperactivity disorder, psychosis, and having any DSM-III-R psychoactive substance use disorder were all significantly more common in the bipolar group than the unipolar depressed group. Comorbid anxiety disorder was present in 40-45% of the subjects in the unipolar and bipolar groups, but in none of the control group subjects.
本研究调查了双相情感障碍青少年中的共病精神障碍。将住院的双相情感障碍青少年(N = 10)与住院的单相抑郁症青少年(N = 33)以及患有非情感性精神障碍的青少年(N = 11)进行比较。结果显示,品行障碍、注意力缺陷多动障碍、精神病以及患有任何《精神疾病诊断与统计手册》第三版修订本中的精神活性物质使用障碍在双相情感障碍组中均比单相抑郁症组更为常见。共病焦虑障碍在单相和双相情感障碍组40% - 45%的受试者中存在,但在对照组受试者中均未出现。