Wang W, Xu S, Zan Z
Department of Obsterics and Gynecology, Zhabei District Central Hospital, Shanghai.
Chin Med J (Engl). 1995 Aug;108(8):576-8.
Parathyrin (PTH) and calcitonin were measured with radioimmunoassay in 39 cases of pregnancy-induced hypertension (PIH) in late pregnancy, 76 cases in normal early pregnancy and 278 cases in late pregnancy without PIH. Markedly increased PTH was noted in the women in late pregnancy, indicating the state of secondary hyperparathyroidism. PTH values in the women in late pregnancy with PIH were higher than those in the normal early pregnancy group, but lower than those in the women in late pregnancy without PIH. The difference between PTH values in the PIH group and late pregnancy without PIH group was of statistical significance (P < 0.05), while no significant difference was seen between calcitonin values of the two groups (P > 0.05). The results suggest that the pathogenesis of PIH may be related to the function of parathyroid.
采用放射免疫法对39例晚期妊娠妊娠期高血压疾病(PIH)患者、76例正常早孕妇女及278例无PIH的晚期妊娠妇女进行甲状旁腺素(PTH)和降钙素测定。晚期妊娠妇女PTH明显升高,提示继发性甲状旁腺功能亢进状态。PIH晚期妊娠妇女的PTH值高于正常早孕组,但低于无PIH的晚期妊娠妇女。PIH组与无PIH晚期妊娠组PTH值差异有统计学意义(P<0.05),而两组降钙素值差异无统计学意义(P>0.05)。结果提示,PIH的发病机制可能与甲状旁腺功能有关。