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[强化化疗后接受自体骨髓移植的急性白血病患者的无病生存期——附11例报告]

[Disease-free survival of acute leukemia patients receiving autologous bone marrow transplant following intensive chemotherapy--a report of 11 cases].

作者信息

Xia X, Lin B, Wu D

机构信息

Jiangsu Institute of Hematology, Suzhou.

出版信息

Zhonghua Zhong Liu Za Zhi. 1995 Jul;17(4):307-10.

PMID:7587904
Abstract

Eleven cases of acute leukemia patients were treated with autologous bone marrow transplantation (ABMT) following intensive chemotherapy with TACC protocol. Among them, eight were in first remission, three in second remission. The median age was 38 years (24-45 years). Bone marrow was purged in vitro before transplantation with procaine and hyperthermia in three cases with acute promyelocytic leukemia. In all patients, ABMT was successful. The results of treatment are as follows: as of May, 1994, the median remission and disease-free survival period was 31 months (6-57), seven cases have been in complete remission for 6-57 months (median 42 months) after treatment and are still alive. In four cases, ABMT was complicated by infection but it was controlled by antibiotics.

摘要

11例急性白血病患者采用TACC方案强化化疗后进行自体骨髓移植(ABMT)。其中,8例处于首次缓解期,3例处于第二次缓解期。中位年龄为38岁(24 - 45岁)。3例急性早幼粒细胞白血病患者在移植前体外采用普鲁卡因和高温清除骨髓。所有患者的ABMT均成功。治疗结果如下:截至1994年5月,中位缓解期和无病生存期为31个月(6 - 57个月),7例患者治疗后完全缓解6 - 57个月(中位42个月)且仍存活。4例患者ABMT后发生感染,但通过抗生素得到控制。

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