Kyriakides Z S, Tousoulis D, Iliodromitis E K, Apostolou T, Michelakakis N, Kremastinos D T
Cardiac Department Onassis Cardiac Surgery Center, Athens, Greece.
Eur Heart J. 1995 Jun;16(6):794-8. doi: 10.1093/oxfordjournals.eurheartj.a060998.
The response of the contralateral arteries was investigated during balloon angioplasty of the left anterior descending artery. Thirty patients were studied. Coronary arteriograms were obtained at baseline, during maximal balloon inflation and at the end of the procedure. Luminal diameter was measured by a quantitative coronary arteriography analysis system. During balloon inflation the luminal diameter of the proximal segment of the right coronary artery increased by 2.4 +/- 6% (P < 0.05), and that of the left circumflex artery increased by 0.6 +/- 6% (P = ns). Both returned to near baseline values after angioplasty. In patients with increased collaterals during balloon inflation the left circumflex proximal segment increased more significantly than in patients with unchanged collaterals. The luminal diameter of the distal segment of the right coronary artery increased by 9 +/- 8% (P < 0.001) and that of the left circumflex artery by 8 +/- 11% (P < 0.01) during balloon inflation, returning to near baseline values after angioplasty. Thus, vasodilation of the contralateral arteries during balloon inflation at the time of coronary angioplasty occurs mainly in the distal segments, and appears to be related to an increase in collateral filling.
在左前降支球囊血管成形术期间，对侧动脉的反应进行了研究。共研究了30例患者。在基线、球囊最大充盈时及手术结束时获取冠状动脉造影。通过定量冠状动脉造影分析系统测量管腔直径。球囊充盈时，右冠状动脉近端节段的管腔直径增加2.4±6%（P<0.05），左旋支动脉的管腔直径增加0.6±6%（P=无显著性差异）。血管成形术后两者均恢复至接近基线值。球囊充盈时侧支循环增加的患者，左旋支近端节段的增加比侧支循环无变化的患者更显著。球囊充盈时，右冠状动脉远端节段的管腔直径增加9±8%（P<0.001），左旋支动脉的管腔直径增加8±11%（P<0.01），血管成形术后恢复至接近基线值。因此，冠状动脉血管成形术时球囊充盈期间对侧动脉的血管舒张主要发生在远端节段，且似乎与侧支循环充盈增加有关。
