Greenough A
Department of Child Health, King's College School of Medicine and Dentistry, London, United Kingdom.
Eur J Pediatr. 1995;154(8 Suppl 3):S2-4. doi: 10.1007/BF02155101.
Research studies have highlighted both physiological and pathological evidence to incriminate surfactant abnormality and/or deficiency in many neonatal respiratory diseases. Data from animal models and clinical studies support the concept that surfactant replacement therapy (SRT) may have a role to play in such problems. There is now, therefore, a need to perform further randomized controlled trials to assess the appropriate clinical application of SRT in non-respiratory distress syndrome neonatal respiratory disease.
研究表明，在许多新生儿呼吸系统疾病中，生理和病理证据均表明表面活性剂异常和/或缺乏是致病因素。来自动物模型和临床研究的数据支持这样一种观点，即表面活性剂替代疗法（SRT）可能在这些问题中发挥作用。因此，现在需要进行进一步的随机对照试验，以评估SRT在非呼吸窘迫综合征新生儿呼吸系统疾病中的适当临床应用。
