• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

用于缓解食管和贲门恶性梗阻的记忆金属支架

Memory metal stents for palliation of malignant obstruction of the oesophagus and cardia.

作者信息

May A, Selmaier M, Hochberger J, Gossner L, Mühldorfer S, Hahn E G, Ell C

机构信息

Department of Medicine I, University of Erlangen-Nuremberg, Germany.

出版信息

Gut. 1995 Sep;37(3):309-13. doi: 10.1136/gut.37.3.309.

DOI:10.1136/gut.37.3.309
PMID:7590422
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1382807/
Abstract

Thirty patients with incurable malignant obstruction of the oesophagus and cardia were treated with self expanding oesophageal memory metal stents (Ultraflex) in a prospective study. The endoprostheses were successfully placed in all patients. Within one week after implantation dysphagia had improved in 25 of 30 patients (83%). Stent expansion was incomplete within one week after implantation in 12 of 30 patients (40%). After an average of two dilatation sessions eight of 12 stents had expanded completely. Five patients complained of retrosternal pain and three of them suffered from heartburn over several days despite acid inhibition. Major problems in the follow up period occurred in 10 of 30 patients (30%) and included late perforation (one) and tumour ingrowth/overgrowth (nine). All of these complications were treated endoscopically. Improvement of the dysphagia of the patients with tumour ingrowth/overgrowth lasted for about eight weeks (median; range: 2-38 weeks). Until November 1994 six of 30 patients were still alive with a survival time of 309 days (median; range: 103-368 days). It is concluded that oesophageal memory metal stents are easy to implant, prove effective in the palliation of malignant oesophageal obstructions, and have a low risk of severe complications. The only disadvantages are that incomplete initial stent expansion as well as tumour ingrowth/overgrowth occurred in nearly one third of the patients.

摘要

一项前瞻性研究中,对30例无法治愈的食管和贲门恶性梗阻患者采用自膨式食管记忆金属支架(Ultraflex)进行治疗。所有患者均成功植入内支架。植入后一周内,30例患者中有25例(83%)吞咽困难得到改善。30例患者中有12例(40%)在植入后一周内支架扩张不完全。平均经过两次扩张治疗后,12个支架中有8个完全扩张。5例患者主诉胸骨后疼痛,其中3例尽管使用了抑酸药物,但仍持续数天出现烧心症状。随访期间,30例患者中有10例(30%)出现严重问题,包括晚期穿孔(1例)和肿瘤长入/过度生长(9例)。所有这些并发症均通过内镜治疗。肿瘤长入/过度生长患者吞咽困难的改善持续约8周(中位数;范围:2 - 38周)。截至1994年11月,30例患者中有6例仍然存活,生存时间为309天(中位数;范围:103 - 368天)。研究得出结论,食管记忆金属支架易于植入,在缓解恶性食管梗阻方面证明有效,且严重并发症风险低。唯一的缺点是近三分之一的患者出现初始支架扩张不完全以及肿瘤长入/过度生长的情况。

相似文献

1
Memory metal stents for palliation of malignant obstruction of the oesophagus and cardia.用于缓解食管和贲门恶性梗阻的记忆金属支架
Gut. 1995 Sep;37(3):309-13. doi: 10.1136/gut.37.3.309.
2
Coated and uncoated self-expanding metal stents for malignant stenosis in the upper GI tract: preliminary clinical experiences with Wallstents.用于上消化道恶性狭窄的覆膜与非覆膜自膨式金属支架:Wallstents的初步临床经验
Am J Gastroenterol. 1994 Sep;89(9):1496-500.
3
[Our experience with the use of a plastic prosthesis and self-expanding stents in the palliative treatment of malignant neoplastic stenoses of the esophagus and cardia. Comparative analysis of results].[我们使用塑料假体和自膨式支架姑息治疗食管和贲门恶性肿瘤狭窄的经验。结果的比较分析]
Chir Ital. 2002 May-Jun;54(3):341-50.
4
[Self-expanding metal stents for palliation of malignant oesophageal obstruction].用于缓解恶性食管梗阻的自膨式金属支架
Magy Seb. 2009 Apr;62(2):59-66. doi: 10.1556/MaSeb.62.2009.2.2.
5
EsophaCoil for palliation of dysphagia in unresectable oesophageal carcinoma: short- and long-term results.用于不可切除食管癌吞咽困难姑息治疗的食管线圈:短期和长期结果
Dig Liver Dis. 2001 Nov;33(8):653-8. doi: 10.1016/s1590-8658(01)80040-2.
6
Endoscopic palliation of unresectable malignant oesophageal strictures with self-expanding metal stents: comparing Ultraflex and Esophacoil stents.使用自膨式金属支架对不可切除的恶性食管狭窄进行内镜下姑息治疗:比较Ultraflex支架和Esophacoil支架
Dig Liver Dis. 2002 May;34(5):356-63. doi: 10.1016/s1590-8658(02)80130-x.
7
Gianturco-Z stents in the palliative treatment of malignant esophageal obstruction and esophagotracheal fistulas.Gianturco-Z支架在恶性食管梗阻和食管气管瘘姑息治疗中的应用
Endoscopy. 1995 Sep;27(7):495-500. doi: 10.1055/s-2007-1005754.
8
Highly flexible self-expanding meshed metal stents for palliation of malignant esophagogastric obstruction.
Endoscopy. 1995 Sep;27(7):486-94. doi: 10.1055/s-2007-1005753.
9
Management of inoperable malignant oesophageal strictures with fully covered WallFlex(®) stent: a multicentre prospective study.使用全覆膜WallFlex(®)支架治疗不可手术切除的恶性食管狭窄:一项多中心前瞻性研究。
Dig Liver Dis. 2014 Dec;46(12):1093-8. doi: 10.1016/j.dld.2014.08.037. Epub 2014 Sep 26.
10
Malignant dysphagia: palliation with esophageal stents--long-term results in 100 patients.恶性吞咽困难:食管支架置入术姑息治疗——100例患者的长期结果
Radiology. 1998 May;207(2):513-8. doi: 10.1148/radiology.207.2.9577503.

引用本文的文献

1
Esophageal stenting.食管支架置入术
Semin Intervent Radiol. 2004 Sep;21(3):157-66. doi: 10.1055/s-2004-860874.
2
Incurable esophageal cancer: patterns of tumor spread and therapeutic consequences.不可治愈的食管癌:肿瘤扩散模式及治疗后果
World J Surg. 2006 Feb;30(2):183-90. doi: 10.1007/s00268-005-7861-6.
3
A rare life-threatening complication of migrated nitinol self-expanding metallic stent (Ultraflex).镍钛诺自膨式金属支架(Ultraflex)移位导致的一种罕见的危及生命的并发症。

本文引用的文献

1
[Nitinol stent in esophageal carcinoma].[镍钛诺支架在食管癌中的应用]
Dtsch Med Wochenschr. 1993 Jan 12;118(1-2):45.
2
A new self-expandable, nickel-titanium coil stent for esophageal obstruction: a preliminary report.一种用于食管梗阻的新型自膨胀镍钛合金线圈支架:初步报告。
Gastrointest Endosc. 1994 Jan-Feb;40(1):64-8. doi: 10.1016/s0016-5107(94)70012-5.
3
A controlled trial of an expansile metal stent for palliation of esophageal obstruction due to inoperable cancer.一项关于可扩张金属支架缓解不可切除癌症所致食管梗阻的对照试验。
Surg Endosc. 2004 Feb;18(2):347. doi: 10.1007/s00464-003-4248-3.
4
Definitive chemoradiotherapy for patients with malignant stricture due to T3 or T4 squamous cell carcinoma of the oesophagus.对因食管T3或T4期鳞状细胞癌导致恶性狭窄的患者进行根治性放化疗。
Br J Cancer. 2003 Jan 13;88(1):18-24. doi: 10.1038/sj.bjc.6600684.
5
Insertion of self-expanding metal stents for malignant dysphagia: assessment of a simple endoscopic method.自膨式金属支架置入术治疗恶性吞咽困难:一种简单内镜方法的评估
Ann R Coll Surg Engl. 2000 Jul;82(4):243-8.
6
Palliation of dysphagia from inoperable oesophageal carcinoma using Atkinson tubes or self-expanding metal stents.使用阿特金森管或自膨式金属支架缓解无法手术的食管癌所致吞咽困难
Ann R Coll Surg Engl. 1998 Nov;80(6):394-7.
7
[1997 gastroenterology update--II].[1997年胃肠病学进展——II]
Med Klin (Munich). 1998 Mar 15;93(3):146-64. doi: 10.1007/BF03044832.
N Engl J Med. 1993 Oct 28;329(18):1302-7. doi: 10.1056/NEJM199310283291803.
4
Malignant esophageal strictures: treatment with a self-expanding nitinol stent.恶性食管狭窄:使用自膨式镍钛合金支架治疗。
Radiology. 1993 Jun;187(3):661-5. doi: 10.1148/radiology.187.3.7684528.
5
Expandable esophageal stents: initial experience with a new nitinol stent.可扩张食管支架:新型镍钛诺支架的初步经验
Gastrointest Endosc. 1994 Sep-Oct;40(5):614-21. doi: 10.1016/s0016-5107(94)70265-9.
6
Coated and uncoated self-expanding metal stents for malignant stenosis in the upper GI tract: preliminary clinical experiences with Wallstents.用于上消化道恶性狭窄的覆膜与非覆膜自膨式金属支架:Wallstents的初步临床经验
Am J Gastroenterol. 1994 Sep;89(9):1496-500.
7
Silicone-covered self-expanding metallic stents for the palliation of malignant esophageal obstruction and esophagorespiratory fistulas: experience in 32 patients and a review of the literature.
Gastrointest Endosc. 1994 Jan-Feb;40(1):22-33. doi: 10.1016/s0016-5107(94)70005-2.
8
Metallic self-expanding stent application in the upper gastrointestinal tract: caveats and concerns.
Gastrointest Endosc. 1992 Jan-Feb;38(1):1-6. doi: 10.1016/s0016-5107(92)70321-6.
9
Implantation of self-expanding esophageal metal stents for palliation of malignant dysphagia.自膨式食管金属支架植入术用于缓解恶性吞咽困难
Endoscopy. 1992 Jun;24(5):405-10. doi: 10.1055/s-2007-1010508.
10
Treatment of malignant esophageal obstruction with silicone-coated metallic self-expanding stents.用硅酮涂层金属自膨式支架治疗恶性食管梗阻
Gastrointest Endosc. 1992 Jan-Feb;38(1):7-11. doi: 10.1016/s0016-5107(92)70322-8.