Gerth K, Schummer D, Höfle G, Irschik H, Reichenbach H
GBF, Gesellschaft für Biotechnologische Forschung Abteilung Naturstoffbiologie, Braunschweig, Federal Republic of Germany.
J Antibiot (Tokyo). 1995 Sep;48(9):973-6. doi: 10.7164/antibiotics.48.973.
An antifungal activity, ratjadon, was detected in the culture broth of Sorangium cellulosum (Myxococcales) strain So ce360. The metabolite was quantitatively bound to the adsorber resin XAD-16, which was added to the medium at the beginning of the fermentation. The antibiotic spectrum was narrow, but some important phytopathogenic fungi, especially species of Oomycetes, were inhibited at very low concentrations.
在纤维堆囊菌(粘球菌目)菌株So ce360的培养液中检测到一种抗真菌活性物质——瑞他君。该代谢产物定量结合于吸附树脂XAD - 16上,XAD - 16在发酵开始时添加到培养基中。其抗菌谱较窄,但一些重要的植物病原真菌,尤其是卵菌纲的一些物种,在极低浓度下就会受到抑制。