Irschik H, Jansen R, Gerth K, Höfle G, Reichenbach H
GBF, Gesellschaft für Biotechnologische Forschung, Departments of Biology of Natural Products, Braunschweig, Germany.
J Antibiot (Tokyo). 1995 Sep;48(9):962-6. doi: 10.7164/antibiotics.48.962.
A new antibiotic, chivosazol, was isolated from the culture broth of the myxobacterium Sorangium cellulosum strain So ce12. It is a macrocyclic ring with one oxazol ring and a glycosidically bound 6-deoxyglucose (quinovose) at C-11. The antibiotic shows antimicrobial activity against yeasts and filamentous fungi, and is especially potent against mammalian cells. It was not active against bacteria.
一种新的抗生素——杀山羊素,是从粘细菌纤维堆囊菌菌株So ce12的培养液中分离出来的。它是一个带有一个恶唑环的大环,在C-11位有一个糖苷键连接的6-脱氧葡萄糖(昆布糖)。该抗生素对酵母和丝状真菌具有抗菌活性,对哺乳动物细胞尤其有效。它对细菌没有活性。