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编码枯草芽孢杆菌乙酰辅酶A羧化酶（脂肪酸合成的第一种酶）的生物素羧基载体蛋白和生物素羧化酶亚基的基因。

The genes encoding the biotin carboxyl carrier protein and biotin carboxylase subunits of Bacillus subtilis acetyl coenzyme A carboxylase, the first enzyme of fatty acid synthesis.

作者信息

Marini P, Li S J, Gardiol D, Cronan J E, de Mendoza D

机构信息

Departamento de Microbiología, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario, Argentina.

出版信息

J Bacteriol. 1995 Dec;177(23):7003-6. doi: 10.1128/jb.177.23.7003-7006.1995.

DOI:10.1128/jb.177.23.7003-7006.1995
PMID:7592499
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC177574/
Abstract

The genes encoding two subunits of acetyl coenzyme A carboxylase, biotin carboxyl carrier protein, and biotin carboxylase have been cloned from Bacillus subtilis. DNA sequencing and RNA blot hybridization studies indicated that the B. subtilis accB homolog which encodes biotin carboxyl carrier protein, is part of an operon that includes accC, the gene encoding the biotin carboxylase subunit of acetyl coenzyme A carboxylase.

摘要

编码乙酰辅酶A羧化酶两个亚基、生物素羧基载体蛋白和生物素羧化酶的基因已从枯草芽孢杆菌中克隆出来。DNA测序和RNA印迹杂交研究表明，编码生物素羧基载体蛋白的枯草芽孢杆菌accB同源物是一个操纵子的一部分，该操纵子包括accC，即编码乙酰辅酶A羧化酶生物素羧化酶亚基的基因。

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1
The genes encoding the biotin carboxyl carrier protein and biotin carboxylase subunits of Bacillus subtilis acetyl coenzyme A carboxylase, the first enzyme of fatty acid synthesis.编码枯草芽孢杆菌乙酰辅酶A羧化酶（脂肪酸合成的第一种酶）的生物素羧基载体蛋白和生物素羧化酶亚基的基因。
J Bacteriol. 1995 Dec;177(23):7003-6. doi: 10.1128/jb.177.23.7003-7006.1995.
2
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本文引用的文献

1
Genes for two subunits of acetyl coenzyme A carboxylase of Anabaena sp. strain PCC 7120: biotin carboxylase and biotin carboxyl carrier protein.鱼腥藻7120菌株乙酰辅酶A羧化酶两个亚基的基因：生物素羧化酶和生物素羧基载体蛋白。
J Bacteriol. 1993 Aug;175(16):5268-72. doi: 10.1128/jb.175.16.5268-5272.1993.
2
Lipid synthesis in mycobacteria: characterization of the biotin carboxyl carrier protein genes from Mycobacterium leprae and M. tuberculosis.分枝杆菌中的脂质合成：麻风分枝杆菌和结核分枝杆菌生物素羧基载体蛋白基因的特性分析
J Bacteriol. 1994 May;176(9):2525-31. doi: 10.1128/jb.176.9.2525-2531.1994.
3
Organization and nucleotide sequences of the genes encoding the biotin carboxyl carrier protein and biotin carboxylase protein of Pseudomonas aeruginosa acetyl coenzyme A carboxylase.铜绿假单胞菌乙酰辅酶A羧化酶中生物素羧基载体蛋白和生物素羧化酶蛋白编码基因的组织与核苷酸序列
J Bacteriol. 1993 Nov;175(21):6881-9. doi: 10.1128/jb.175.21.6881-6889.1993.
4
Role of pyruvate carboxylase, phosphoenolpyruvate carboxykinase, and malic enzyme during growth and sporulation of Bacillus subtilis.丙酮酸羧化酶、磷酸烯醇式丙酮酸羧激酶和苹果酸酶在枯草芽孢杆菌生长和孢子形成过程中的作用
J Biol Chem. 1973 Sep 10;248(17):6062-70.
5
Sequence homology around the biotin-binding site of human propionyl-CoA carboxylase and pyruvate carboxylase.人丙酰辅酶A羧化酶和丙酮酸羧化酶生物素结合位点周围的序列同源性。
Arch Biochem Biophys. 1987 May 1;254(2):631-6. doi: 10.1016/0003-9861(87)90146-9.
6
Sequence analysis, biogenesis, and mitochondrial import of the alpha-subunit of rat liver propionyl-CoA carboxylase.大鼠肝脏丙酰辅酶A羧化酶α亚基的序列分析、生物合成及线粒体导入
J Biol Chem. 1989 Jul 25;264(21):12680-5.
7
The E. coli bio operon: transcriptional repression by an essential protein modification enzyme.
Cell. 1989 Aug 11;58(3):427-9. doi: 10.1016/0092-8674(89)90421-2.
8
A system for rapid DNA sequencing with fluorescent chain-terminating dideoxynucleotides.一种使用荧光链终止双脱氧核苷酸进行快速DNA测序的系统。
Science. 1987 Oct 16;238(4825):336-41. doi: 10.1126/science.2443975.
9
Direct and general selection for lysogens of Escherichia coli by phage lambda recombinant clones.通过噬菌体λ重组克隆对大肠杆菌溶原菌进行直接和通用筛选。
J Bacteriol. 1991 Jun;173(12):3724-31. doi: 10.1128/jb.173.12.3724-3731.1991.
10
cis-unsaturated fatty acids specifically inhibit a signal-transducing protein kinase required for initiation of sporulation in Bacillus subtilis.
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