Kumar U T, Vela N P, Caruso J A
University of Cincinnati, Department of Chemistry, Ohio 45221-0172, USA.
J Chromatogr Sci. 1995 Nov;33(11):606-10. doi: 10.1093/chromsci/33.11.606.
Organometal compounds of arsenic, antimony, and mercury are speciated using supercritical fluid chromatography with inductively coupled plasma mass spectrometric (ICP-MS) detection. The multi-element capability of ICP-MS for transient signals is examined by detecting five compounds containing all three elements in a single chromatographic injection. The results obtained are compared with those obtained from flame-ionization detection (FID). Trimethyl arsine is not distinguished from the solvent peak when FID is used because it coelutes with the solvent, whereas trimethyl arsine is detected when ICP-MS is used because of its element-selective nature. The detection limits obtained by ICP-MS are 2-3 orders of magnitude lower than those obtained by FID. Determination of isotope abundance is also demonstrated for triphenyl antimony and diphenyl mercury compounds.
采用超临界流体色谱-电感耦合等离子体质谱（ICP-MS）检测法对砷、锑和汞的有机金属化合物进行形态分析。通过在一次色谱进样中检测包含所有三种元素的五种化合物，考察了ICP-MS对瞬态信号的多元素检测能力。将所得结果与火焰离子化检测（FID）所得结果进行比较。使用FID时，三甲基砷与溶剂峰无法区分，因为它与溶剂共洗脱，而使用ICP-MS时，由于其元素选择性，三甲基砷可被检测到。ICP-MS获得的检测限比FID获得的检测限低2 - 3个数量级。还展示了对三苯基锑和二苯基汞化合物的同位素丰度测定。
