Kazem R, Thompson L A, Hamilton M P, Templeton A
University Department of Obstetrics and Gynaecology, Aberdeen Maternity Hospital, UK.
Hum Reprod. 1995 Jun;10(6):1543-8. doi: 10.1093/humrep/10.6.1543.
Recent widespread concern has led to legislation in the UK preventing the use of fetal ovarian tissue for the treatment of infertile women. This questionnaire-based study aimed to assess the attitudes of both fertile and infertile men and women as well as egg donors and recipients towards the use of donated eggs for treatment, diagnosis and research. Fertile individuals were significantly less aware of egg donation but the majority in both the fertile and the infertile groups approved the use of eggs for research (89 and 95% of women and 88 and 92% of men respectively) and treatment (similar percentages). However, fetal sources of oocytes were acceptable to only 15% of women in the fertile, 21% in the infertile, 35% in the recipient and 19% in the donor groups. Cadaveric sources of oocytes were slightly more acceptable (28% fertile, 28% infertile, 50% recipient and 42% donors). Both these sources of oocytes were slightly more acceptable to men. Education had little influence on attitudes, although men and women of tertiary education level said they would be less likely to have gamete donation themselves. Thus there would appear to be widespread approval for the use of donor eggs in research and treatment but not if the source of eggs is fetal or cadaveric.
近期广泛的关注促使英国出台立法，禁止使用胎儿卵巢组织治疗不孕女性。这项基于问卷调查的研究旨在评估有生育能力和不孕的男性与女性以及卵子捐赠者和接受者对使用捐赠卵子进行治疗、诊断和研究的态度。有生育能力的个体对卵子捐赠的了解明显较少，但有生育能力和不孕群体中的大多数人都赞成将卵子用于研究（分别为89%和95%的女性以及88%和92%的男性）和治疗（比例相似）。然而，在有生育能力的女性群体中，只有15%的人接受胎儿来源的卵母细胞，不孕女性群体中这一比例为21%，接受者群体中为35%，捐赠者群体中为19%。尸体来源的卵母细胞接受度略高一些（有生育能力的群体中为28%，不孕群体中为28%，接受者群体中为50%，捐赠者群体中为42%）。男性对这两种卵母细胞来源的接受度略高。教育对态度影响不大，尽管受过高等教育的男性和女性表示他们自己进行配子捐赠的可能性较小。因此，对于在研究和治疗中使用捐赠卵子似乎普遍得到认可，但如果卵子来源是胎儿或尸体则不然。
