Staindl O, Lametschwandtner A, Zimmermann G, Adam H
HNO. 1979 Jan;27(1):7-13.
In the present study, 7 x 15 mm Cialit-preserved human tracheal segments were grafted to the tracheas of five 3-month old piglets. 72-120 days later, the animals were sacrificed and the grafts with proximal and distal control areas were removed. Tissues were then examined macroscopically and by light and scanning electron microscopy. We found that: (1) all grafts had taken well; (2) no animal suffered from clinical signs of respiratory obstruction or inflammation; (3) although luminal diameters of the tracheas increased from 8 mm to 22 mm, the size of the grafts remained unchanged but the resulting tracheal stenosis did not cause respiratory obstruction; (4) the graftet areas showed re-epithelialization. The nature of the re-epithelialization as well as the fate of the submucosa and tracheal cartilage will be reported in a subsequent publication.
在本研究中，将7×15毫米经西阿尔特（Cialit）保存的人气管段移植到5只3月龄仔猪的气管中。72至120天后，处死动物并取出带有近端和远端对照区域的移植物。然后对组织进行宏观检查以及光镜和扫描电镜检查。我们发现：（1）所有移植物均生长良好；（2）没有动物出现呼吸阻塞或炎症的临床症状；（3）尽管气管的管腔直径从8毫米增加到了22毫米，但移植物的大小保持不变，并且由此产生的气管狭窄并未导致呼吸阻塞；（4）移植区域出现了重新上皮化。重新上皮化的性质以及黏膜下层和气管软骨的命运将在后续出版物中报道。
