Johnston B T, Lewis S A, Love A H
Department of Medicine, Royal Victoria Hospital, Belfast, UK.
J Psychosom Res. 1995 Feb;39(2):221-6. doi: 10.1016/0022-3999(94)00102-b.
In 40% of patients presenting to medical clinics with heartburn, no objective evidence of gastro-oesophageal reflux disease can be demonstrated. Little research has been performed regarding the psychological characteristics of these patients. The aim of this study was to assess the psycho-social profiles of patients presenting with heartburn in an attempt to discriminate between those with pathological reflux and those with functional disease.
One hundred and thirty-eight patients presenting with heartburn underwent endoscopy and oesophageal pH monitoring. They were divided into those with oesophagitis or abnormal degrees of acid reflux into the oesophagus and those with normal endoscopy and normal pH profile. The psychological questionnaires used were the Hassles Scale, the State-Trait Anxiety Index, the Crown-Crisp Experiential Index and the Interview Schedule for Social Interaction.
Patients with functional heartburn did not report any increase in daily hassles nor did they have higher levels of anxiety, depression or other psychological characteristics than those with objective reflux disease. In terms of their available social support, the two groups were similar.
Differences in psychological characteristics and social support structures do not offer an explanation for the heartburn experienced by patients in the absence of objective evidence of reflux disease. Other explanations, including visceral hypersensitivity, should be sought in these patients.
在因烧心症状前往诊所就诊的患者中,40%并无胃食管反流病的客观证据。针对这些患者的心理特征,此前几乎未开展过研究。本研究旨在评估烧心患者的心理社会状况,以区分病理性反流患者和功能性疾病患者。
138名烧心患者接受了内窥镜检查和食管pH监测。他们被分为患有食管炎或食管酸反流程度异常的患者,以及内窥镜检查和pH值正常的患者。所使用的心理问卷包括烦恼量表、状态-特质焦虑指数、克朗-克里斯普体验指数和社会交往访谈量表。
功能性烧心患者并未报告日常烦恼有所增加,与有客观反流病的患者相比,他们在焦虑、抑郁或其他心理特征方面也没有更高水平。在可获得的社会支持方面,两组相似。
心理特征和社会支持结构的差异并不能解释在没有反流病客观证据的情况下患者所经历的烧心症状。对于这些患者,应寻求其他解释,包括内脏高敏感性。