Johnson H, Belluco C, Masood S, Azama A, Kahn L, Wise L
Department of Surgery, Long Island Jewish Medical Center, New Hyde Park, New York, USA.
J Natl Med Assoc. 1995 Jun;87(6):423-6.
This study was undertaken to investigate the ability of local anatomical and primary histological features of gastric cancers, as well as DNA analysis, to predict prognosis. Using multivariate analysis, results indicate that location of a tumor in the gastric cardia, poor differentiation, involvement of adjacent organs, and aneuploidy are all independent predictors of survival. All of the factors studied can be determined by endoscopic procedures preoperatively on patients with gastric cancers and could be helpful in selecting some patients for perioperative adjunctive therapies.
本研究旨在探讨胃癌的局部解剖学和原发性组织学特征以及DNA分析预测预后的能力。通过多变量分析，结果表明肿瘤位于胃贲门、分化差、累及相邻器官和非整倍体都是生存的独立预测因素。所有研究的因素都可以通过对胃癌患者术前的内镜检查来确定，并且有助于为一些患者选择围手术期辅助治疗。
