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长期脊髓刺激后人类的疼痛感知

Pain perception in man after long term spinal cord stimulation.

作者信息

Doerr M, Krainick J U, Thoden U

出版信息

J Neurol. 1978 Mar 9;217(4):261-70. doi: 10.1007/BF00312987.

Abstract

Thresholds of non-painful and painful perception for electrical stimuli are not altered significantly during dorsal column stimulation either in the area of induced paresthesia or outside it. After long term stimulation of the dorsal column the thresholds for stimuli are significantly higher within the area of induced paresthesia but not outside it. Median nerve evoked somatosensory cortical potentials are not altered by conditioning or simultaneous DC stimulation. During DCS in three of eight patients only the vibration evoked cortical potentials were attenuated in the early three components of the potential.

摘要

在背柱刺激期间,无论是在诱发感觉异常的区域内还是区域外,电刺激的无痛觉和痛觉阈值均未发生显著改变。在背柱长期刺激后,诱发感觉异常区域内的刺激阈值显著升高,但区域外则不然。正中神经诱发的体感皮层电位不会因条件刺激或同时进行的背柱刺激而改变。在八名患者中的三名进行背柱刺激期间,仅在电位的早期三个成分中,振动诱发的皮层电位有所衰减。

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