Blair R D, Lee R G, Vanderlinden G
Arch Neurol. 1975 Dec;32(12):826-9. doi: 10.1001/archneur.1975.00490540070009.
Several authors have shown that dorsal column stimulation (DCS) modifies appreciation of pain. We studied the effects of DCS on the somatosensory evoked response (SER) in six subjects. Somatosensory evoked responses to stimulation of the tibial nerve and effects of varying frequencies and intensities of DCS on SER components were recorded. During DCS there was attenuation of late SER components with little effect on early components. Stimulus intensities greater than necessary to relieve pain suppressed all SER components. Our findings suggest that the minimal effective DCS variables to relieve pain are those that produce selective suppression of late SER components.
几位作者已经表明,脊髓后柱刺激(DCS)会改变对疼痛的感知。我们研究了DCS对6名受试者体感诱发电位(SER)的影响。记录了对胫神经刺激的体感诱发电位以及不同频率和强度的DCS对SER成分的影响。在DCS期间,SER晚期成分减弱,而对早期成分影响不大。大于缓解疼痛所需的刺激强度会抑制所有SER成分。我们的研究结果表明,缓解疼痛的最小有效DCS变量是那些能选择性抑制SER晚期成分的变量。