Hasan A, Corris P A, Healy M, Wrightson N, Gascoigne A D, Waller D A, Wilson I, Hilton C J, Gould F K, Forty J
Department of Cardiothoracic Surgery, Freeman Hospital, Newcastle upon Tyne, UK.
Thorax. 1995 May;50(5):565-6. doi: 10.1136/thx.50.5.565.
Bilateral sequential lung transplantation (BSLT) has been widely adopted as an alternative to combined heart and lung transplantation for the management of end stage septic lung disease in many transplant centres.
A retrospective review was undertaken of the first 32 consecutive patients with septic lung disease to undergo BSLT at the Freeman Hospital.
Between April 1988 and October 1994 32 patients underwent BSLT. Survival at 30 days was 85% and actuarial survival at one year was 70%. Improved pulmonary function was seen in all surviving patients.
BSLT for septic lung disease offers comparable survival to heart-lung transplantation, with excellent functional results. Long term results may be superior because the disadvantages of transplanting the heart are avoided.
在许多移植中心,双侧序贯肺移植(BSLT)已被广泛采用,作为心肺联合移植的替代方法,用于治疗终末期感染性肺病。
对弗里曼医院连续接受BSLT的首批32例感染性肺病患者进行了回顾性研究。
1988年4月至1994年10月期间,32例患者接受了BSLT。30天生存率为85%,一年预期生存率为70%。所有存活患者的肺功能均有改善。
感染性肺病的BSLT与心肺移植的生存率相当,功能结果良好。由于避免了心脏移植的缺点,长期结果可能更好。