Turley K, Szarnicki R J, Flachsbart K D, Richter R C, Popper R W, Tarnoff H
California Pacific Medical Center, Kaiser Permanente Medical Center, San Francisco 94115, USA.
Ann Thorac Surg. 1995 Jul;60(1):84-9.
Anomalous origin of the left coronary artery from the pulmonary artery (PA) optimally is treated by creation of a multiple coronary system. This study explores the use of aortic implantation employing alternative methods to achieve coronary transfer in all patients, regardless of the site of origin of the anomalous coronary artery, avoiding the problems of bypass grafts and tunnel procedures.
During the period 1986 to 1994, 11 patients aged 6 months to 8 years (mean age, 2.6 years) underwent repair. Coronary artery origin from the PA included left sinus in 3, posterior in 2, right sinus in 2, intramural aorta with its orifice at the bifurcation of the main and right PA in 1, high left main PA in 1, high at the bifurcation of main and right PA in 1, and anterior in 1. Findings included angina in 4, prior infarctions in 3, ischemia in 7, left ventricular dysfunction in 6, mitral regurgitation in 5, atrial septal defect in 2, and echocardiograms suggestive of endocardial fibrosis in 4. One patient had prior ligation with ventricular dysfunction and collateralization and recanalization. A single patient was asymptomatic. Repair was accomplished by direct transfer using the PA sinus of Valsalva as a button in only 6; tubular reconstruction was used in 4 when the distance was too great to avoid tension; 2 short tubes were constructed with PA wall in 2 of the 3 left sinus origins, whereas 2 long tubes of PA wall were used (1 high on the left side of the main PA and 1 with left anterior descending origin from the anterior sinus of Valsalva in a patient with malrotation [end neo-artery to side aortic reconstruction]); finally, in situ transfer and intraaortic reconstruction (unroofing and anastomosis) was performed in 1 intramural coronary artery. Division of the PA, mobilization of the distal PA, division of the ductus, and direct reanastomosis of the PA was performed in 3 tubular reconstructions, as well as all 6 direct coronary transfers.
There were no operative or late deaths. Follow-up of 2 to 100 months (mean, 46 months) revealed no new angina or infarctions, improved function and decreased mitral regurgitation. Echocardiographic and angiographic studies demonstrated patency and prograde flow in the new coronary systems.
Aortic implantation is the treatment of choice for anomalous origin of the left coronary artery. Methods such as direct transfer, tubular reconstruction, and in situ transfer make such implantation possible in all patients regardless of the site of coronary origin, distance from the aorta, or coronary artery configuration.
左冠状动脉起源于肺动脉(PA)的异常情况,最佳治疗方法是构建多冠状动脉系统。本研究探讨采用主动脉植入的替代方法,使所有患者的冠状动脉得以转移,无论异常冠状动脉的起源部位如何,避免旁路移植和隧道手术的问题。
在1986年至1994年期间,11例年龄在6个月至8岁(平均年龄2.6岁)的患者接受了修复手术。冠状动脉起源于肺动脉的情况包括:3例起源于左窦,2例起源于后窦,2例起源于右窦,1例起源于主动脉壁内且开口位于主肺动脉和右肺动脉分叉处,1例起源于左主肺动脉高位,1例起源于主肺动脉和右肺动脉分叉处高位,1例起源于前窦。发现的情况包括:4例有心绞痛,3例有既往心肌梗死,7例有心肌缺血,6例有左心室功能障碍,5例有二尖瓣反流,2例有房间隔缺损,4例超声心动图提示心内膜纤维化。1例患者既往曾行结扎术,伴有心室功能障碍、侧支循环形成及再通。1例患者无症状。仅6例通过使用瓦尔萨尔瓦窦(Valsalva窦)作为纽扣进行直接转移完成修复;4例因距离过大无法避免张力时采用管状重建;3例左窦起源中的2例用肺动脉壁构建了2根短管,而另外2例使用了肺动脉壁的长管(1例在主肺动脉左侧高位,1例在旋转不良患者中左前降支起源于瓦尔萨尔瓦前窦[最终新动脉至主动脉侧重建]);最后,1例壁内冠状动脉采用原位转移和主动脉内重建(开窗和吻合)。3例管状重建以及所有6例直接冠状动脉转移均进行了肺动脉切断、远端肺动脉游离、动脉导管切断及肺动脉直接再吻合。
无手术死亡或晚期死亡。随访2至100个月(平均46个月),未发现新的心绞痛或心肌梗死,功能改善,二尖瓣反流减少。超声心动图和血管造影研究显示新冠状动脉系统通畅且血流呈正向。
主动脉植入是左冠状动脉起源异常的首选治疗方法。直接转移、管状重建和原位转移等方法使所有患者无论冠状动脉起源部位、与主动脉的距离或冠状动脉形态如何,均可进行这种植入。