Chelomin V P, Bobkova E A, Lukyanova O N, Chekmasova N M
Pacific Oceanological Institute, Russian Academy of Sciences, Vladivostok.
Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1995 Mar;110(3):329-35. doi: 10.1016/0742-8413(95)95345-c.
Studies were performed regarding the effect of cadmium accumulation on the levels of essential elements (copper, zinc and iron) in the tissues of a marine bivalve mollusc, Mizuhopecten yessoensis, exposed to cadmium at 250 ppb during 2 weeks. It was found that the concentration of cadmium in the tissues increased in the order gonads < gills < hepatopancreas < kidney during exposure time. However, the highest value of concentration factor was recorded in the gills. Our data demonstrate that cadmium accumulation in all mollusc tissues is followed by the alterations in copper, zinc and iron concentration, but that the pattern of these changes varies with each tissue. Cadmium had the most pronounced effects on essential trace element homeostasis in the kidney. The present study suggests that levels of the essential metals in a particular tissue can be modified depending on the level of cadmium accumulation. The possible mechanisms of the effects of cadmium on the essential trace elements are discussed.
针对海洋双壳贝类软体动物虾夷扇贝在250 ppb镉浓度下暴露2周后，镉积累对其组织中必需元素（铜、锌和铁）水平的影响进行了研究。结果发现，在暴露期间，组织中镉的浓度按性腺＜鳃＜肝胰腺＜肾脏的顺序增加。然而，鳃中的浓缩系数最高。我们的数据表明，所有软体动物组织中镉的积累都会伴随着铜、锌和铁浓度的变化，但这些变化模式因组织而异。镉对肾脏中必需微量元素稳态的影响最为显著。本研究表明，特定组织中必需金属的水平可根据镉积累水平而改变。文中还讨论了镉对必需微量元素影响的可能机制。
