一名患有滑膜炎、痤疮、脓疱病、骨肥厚和骨髓炎综合征（SAPHO综合征）的患者发生了髂骨骨肉瘤。

Iliac osteosarcoma in a patient with SAPHO syndrome.

作者信息

Legrand E, Audran M, Rousselet-Chapeau M C, Le Levier F, Brithmer L, Vigouroux B, Pidhorz L, Brégeon C

机构信息

Department of Rheumatology, Angers Teaching Hospital, France.

出版信息

Rev Rhum Engl Ed. 1995 Feb;62(2):139-41.

PMID:7600067

Abstract

Extrathoracic sclerotic bone involvement of SAPHO syndrome are sometimes very difficult to differentiate from a bone infection or bone tumor. The authors report the case of a 46-year-old patient with a history of palmo-plantar pustulosis, recurrent suppurative hidradenitis, and bilateral sternocostal arthropathy who was evaluated for a sclerotic lesion in an iliac wing. The clinical course, computed tomography findings, and histologic features of a surgical biopsy specimen established the diagnosis of osteoblastic osteosarcoma with SAPHO syndrome.

摘要

SAPHO综合征的胸外硬化性骨受累有时很难与骨感染或骨肿瘤相鉴别。作者报告了一例46岁患者，有掌跖脓疱病、复发性化脓性汗腺炎和双侧胸肋关节病病史，因髂骨翼硬化性病变接受评估。手术活检标本的临床病程、计算机断层扫描结果和组织学特征确诊为伴有SAPHO综合征的成骨性骨肉瘤。