Sanjuán Portugal F, Manero Ruiz F J, Figueras Villalba P, Martínez Alvarez R
Servicio de Medicina Interna, Hospital Miguel Servet, Zaragoza.
Rev Clin Esp. 1995 Apr;195(4):233-6.
SAPHO syndrome is characterized by osteoarticular involvement of ventral chest wall in the form of sternocostoclavicular osteoarthritis and hyperostosis and skin changes such as palmoplantar pustulosis and acne. Occasionally, psoriatic lesions and sacroiliitis are observed. However, despite the higher frequency of psoriasis in this syndrome, its inclusion in psoriatic arthropathy spectrum is not clearly established. The authors report three cases of SAPHO syndrome in psoriatic patients commenting on the difficulty in differentiating this entity from psoriatic arthritis as well as its relationship with seronegative spondyloarthropathies. This disease has been described mainly in Japan and only a few cases of this disease have been reported in the European or American literature.
SAPHO综合征的特征是前胸壁以胸锁关节骨关节炎和骨质增生的形式出现骨关节受累,以及皮肤改变,如掌跖脓疱病和痤疮。偶尔也会观察到银屑病皮损和骶髂关节炎。然而,尽管该综合征中银屑病的发病率较高,但它是否属于银屑病关节炎范畴尚未明确确定。作者报告了3例银屑病患者的SAPHO综合征病例,并阐述了将该疾病与银屑病关节炎区分开来的困难以及它与血清阴性脊柱关节病的关系。这种疾病主要在日本被描述过,欧美文献中仅报道过少数病例。