Anderson L E, Myer R O, Brendemuhl J H, McDowell L R
Animal Science Department, University of Florida, Gainesville 32611, USA.
J Anim Sci. 1995 Feb;73(2):490-5. doi: 10.2527/1995.732490x.
Relative bioavailabilities of four chemical forms of vitamin E were evaluated when supplemented in diets of finishing swine for 28 d. Forty crossbred pigs (80 kg), individually penned, were divided equally among five treatments. Treatments consisted of corn soybean meal-based diets supplemented with DL-alpha-tocopherol, DL-alpha-tocopheryl acetate, D-alpha-tocopherol, or D-alpha-tocopheryl acetate. A treatment without vitamin E supplementation (negative control) served as the fifth treatment. Each compound was supplemented at 62 IU/kg of diet. Blood samples were collected on d 0, 1, 2, 7, 14, 21, and 28. On d 29, half the pigs were slaughtered to obtain tissue samples. Feed samples, taken from feeders, were also collected on d 0, 5, 14, and 21. All vitamin E forms fed increased (P < .01) serum alpha-tocopherol by d 2 and peaked by d 7. Serum alpha-tocopherol in pigs fed either acetate form remained elevated beyond d 7; serum alpha-tocopherol steadily declined and was lower (P < .01) on d 14, 21, and 28 in pigs fed either alcohol form compared with concentrations in the acetate-fed pigs. The decrease was probably a reflection of poor stability of the alcohol forms observed in the feed; the acetate forms were found to be stable in the feed over the 28-d study. Dietary supplementation of D-alpha-tocopheryl acetate resulted in the highest serum alpha-tocopherol throughout the study. A similar trend was observed in tissue (liver, backfat, leaf fat, semimembranosus, rhomboideus) alpha-tocopherol and serum: the liver had the highest concentration.(ABSTRACT TRUNCATED AT 250 WORDS)
在育肥猪日粮中添加四种化学形式的维生素E 28天，评估其相对生物利用率。40头杂交猪（80千克），单栏饲养，平均分为五个处理组。处理组日粮以玉米豆粕为基础，分别添加DL-α-生育酚、DL-α-生育酚乙酸酯、D-α-生育酚或D-α-生育酚乙酸酯。不添加维生素E的处理组（阴性对照）作为第五个处理组。每种化合物的添加量均为62 IU/kg日粮。在第0、1、2、7、14、21和28天采集血样。在第29天，宰杀一半的猪以获取组织样本。在第0、5、14和21天也采集来自饲槽的饲料样本。所有添加的维生素E形式在第2天时均使血清α-生育酚增加（P < .01），并在第7天达到峰值。饲喂乙酸酯形式的猪血清α-生育酚在第7天后仍保持升高；与饲喂乙酸酯形式的猪相比，饲喂醇形式的猪血清α-生育酚在第14、21和28天稳步下降且较低（P < .01）。这种下降可能反映了饲料中醇形式的稳定性较差；在为期28天的研究中发现乙酸酯形式在饲料中是稳定的。在整个研究中，日粮添加D-α-生育酚乙酸酯导致血清α-生育酚水平最高。在组织（肝脏、背膘、板油、半膜肌、菱形肌）α-生育酚和血清中观察到类似趋势：肝脏中的浓度最高。（摘要截短至250字）
