丁型肝炎病毒的分子生物学与发病机制分析
Molecular biologic and pathogenetic analysis of hepatitis delta virus.
作者信息
Lai M M
机构信息
Howard Hughes Medical Institute, University of Southern California, School of Medicine, Los Angeles 90033, USA.
出版信息
J Hepatol. 1995;22(1 Suppl):127-31.
PMID:7602064
Abstract
Hepatitis delta virus (HDV) consists of an envelope derived from hepatitis B virus (HBV) and a nucleocapsid consisting of hepatitis delta antigen and a circular RNA genome. Both the delta antigen and the RNA possess many unique properties which play crucial roles in the life cycle of HDV. They may also contribute indirectly to the mechanism of viral pathogenesis.
摘要
丁型肝炎病毒（HDV）由源自乙型肝炎病毒（HBV）的包膜和由丁型肝炎抗原及环状RNA基因组组成的核衣壳构成。丁型肝炎抗原和RNA都具有许多独特特性，这些特性在HDV的生命周期中发挥着关键作用。它们也可能间接促成病毒致病机制。
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