丁型肝炎病毒：分子生物学、发病机制与免疫学
Hepatitis delta virus: molecular biology, pathogenesis and immunology.
作者信息
Casey J L
机构信息
Division of Molecular Virology and Immunology, Georgetown University Medical Center, Rockville, Maryland, USA.
出版信息
Antivir Ther. 1998;3(Suppl 3):37-42.
PMID:10726054
Abstract
Hepatitis delta virus (HDV) is a unique infectious agent which causes severe liver disease in those infected with its helper virus, hepatitis B virus. No effective antiviral therapy for HDV exists. This review covers recent advances in the molecular biology, pathogenesis and immunology of HDV, with an emphasis on potential targets for the development of successful antiviral agents.
摘要
丁型肝炎病毒（HDV）是一种独特的感染因子，可在感染其辅助病毒乙型肝炎病毒的人群中引发严重肝脏疾病。目前尚无针对HDV的有效抗病毒疗法。本综述涵盖了HDV分子生物学、发病机制和免疫学方面的最新进展，重点关注成功开发抗病毒药物的潜在靶点。
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